Research Articles
Dietary Proteins and Amino Acids in Glucose Homeostasis: Molecular Mechanisms, Clinical Applications, and Therapeutic Potential
This article synthesizes current evidence on the complex, dual role of dietary proteins and amino acids in regulating glucose metabolism.
From Glucose to ATP: Molecular Mechanisms, Metabolic Regulation, and Therapeutic Targeting
This article provides a comprehensive analysis of the molecular machinery and regulatory networks governing cellular glucose uptake and utilization for ATP production.
From Amino Acids to Glucose: Molecular Mechanisms, Regulatory Networks, and Therapeutic Targeting of Hepatic Gluconeogenesis
This article provides a comprehensive analysis of the gluconeogenesis pathway, with a specialized focus on the conversion of glucogenic amino acids into glucose.
Thyroid Hormones T3 and T4 as Central Regulators of Basal Metabolic Rate: Molecular Mechanisms, Metabolic Integration, and Therapeutic Potential
Thyroid hormones (THs), thyroxine (T4) and triiodothyronine (T3), are primary determinants of mammalian basal metabolic rate (BMR), regulating energy expenditure, thermogenesis, and the metabolism of carbohydrates, lipids, and proteins across...
The Inflammatory Signal: How a Single Protein May Hold the Key to Diabetic Foot Ulcers
Discover how APOE pro-inflammatory signaling contributes to diabetic foot ulcers through groundbreaking single-cell research
The Red Revolution: How Astaxanthin Tames Inflammation in Type 2 Diabetes
Discover how astaxanthin, a powerful natural antioxidant, modulates inflammation in Type 2 diabetes through regulation of microRNAs and metabolic markers.
The Tiny Messengers Offering New Hope for Type 2 Diabetes
Discover how stem cell-derived extracellular vesicles combat oxidative damage in Type 2 Diabetes through the miR-191-5p/DAPK1/AKT pathway
The Root of a New Solution: How a Humble Herb's Sugar Could Help Fight Diabetes
Discover how Pseudostellaria heterophylla polysaccharide improves insulin resistance through gut-liver axis communication and PI3K/AKT signaling pathways.
The Genetic Master Key: How KLF14 Unlocks Metabolic Health Secrets
Explore how KLF14 genetic variations function as master regulators in metabolic diseases, with sex-specific effects and therapeutic potential.
The Future of Diabetes Care: Exploring the Potential of Bioartificial Pancreas and DIY APS Innovations
Discover how bioartificial pancreas technology and DIY artificial pancreas systems are revolutionizing diabetes care through innovative approaches to insulin regulation.