Research Articles
How Cisplatin Fights Cancer: DNA Damage and Metabolic Starvation
Discover how cisplatin suppresses cancer growth through dual mechanisms - DNA damage and inhibition of integrin β5-mediated glycolysis in breast and cervical cancers.
When Diabetes Stresses the Heart: A New Era of Treatment
Exploring the bidirectional relationship between diabetes and heart failure, and the revolutionary treatments transforming patient care.
The Brain's Water Switch: How a Single Neurotransmitter Controls Fluid Balance
Discover how GABA neurotransmitter controls vasopressin release and fluid balance in the brain through groundbreaking neuroscience research.
Unlocking Dairy Heifer Potential: The Stair-Step Growth Revolution
Discover how the stair-step growth pattern revolutionizes dairy heifer rearing through compensatory growth, improving efficiency and milk production.
The Misfiring Engine: How Your Thyroid's Subtle Signals Might Be Pushing You Toward Prediabetes
Discover how sensitivity to thyroid hormones within the normal range can significantly influence your risk of developing prediabetes in this comprehensive scientific analysis.
The Fat Controller: How a 'Good' Hormone Puts the Brakes on Fat Breakdown
Explore the fascinating role of adiponectin in fat metabolism and how this 'good' hormone inhibits lipolysis through AMPK-dependent mechanisms.
The Kidney's Hidden Guardian: How a Newly Discovered Cellular Pathway Could Revolutionize Diabetic Nephropathy Treatment
Discover how RUNX3-activated apelin signaling inhibits cell proliferation and fibrosis in diabetic nephropathy through regulation of the SIRT1/FOXO pathway
The Sugar Gatekeeper: How E. Coli Controls Its Sweet Tooth
Explore how E. coli regulates rhamnose metabolism through the rhaT gene and its sophisticated genetic switchboard system.
The Sweet Sabotage: How Our Bodies Balance Glucose, Fat, and Insulin in Diabetes
Exploring how palmitate and insulin counteract glucose-induced TXNIP expression through distinct molecular mechanisms in pancreatic beta cells.
The Hidden Geography of the Liver: How Your Liver's Map Guides Metabolism
Exploring the spatial organization of enzymes and metabolic heterogeneity in liver lobules and their role in glucose homeostasis.