Discover how sodium butyrate fights cancer by targeting GLUT1 sugar transporters and inducing apoptosis in HT-29 cancer cells.
Discover how Akt-directed glucose metabolism prevents Bax conformation change and promotes cancer cell survival, opening new therapeutic possibilities.
Discover how cancer causes insulin resistance in skeletal muscle through TNF-α expression and leads to cachexia in cancer patients.
Scientists discover how 4EBP1 and 4EBP2 proteins help cancer cells survive energetic stress by regulating fatty acid synthesis, revealing new therapeutic targets.
Groundbreaking research challenges cancer metabolism dogma by creating glycolytic-null cancer cells that survive without fermentative glycolysis through metabolic reprogramming.
Scientists are decoding the unique structure of hexokinase 2, a key metabolic enzyme in cancer, to develop smarter, more targeted therapies.
Discover how scientists are using genetic scissors to target cancer's sugar addiction and develop new treatments for lung cancer.
Exploring how targeting tumor glycolysis through the Warburg effect is transforming cancer treatment approaches.