Explore how TXNIP protein contributes to pancreatic beta cell dysfunction in diabetes through impaired glucose tolerance and hypertriglyceridemia.
Explore the fascinating science behind glucokinase, the body's glucose sensor, and how its mutations cause MODY2 diabetes through detailed structural and functional analysis.
Explore the fascinating process of insulin gene expression during pancreatic islet cell development and its implications for diabetes research.
Discover how the HID-1 protein regulates blood glucose through secretory granule maturation and its implications for diabetes research.
Discover how KATP channels function as biological thermostats regulating insulin secretion and their role in diabetes treatment breakthroughs.
Discover how Menaquinone-4 (MK-4), a form of Vitamin K2, amplifies glucose-stimulated insulin secretion in pancreatic cells and its potential implications for diabetes research.
Discover how miR-424-5p, a tiny molecule, protects retinal cells from high glucose damage and could prevent diabetic retinopathy.
Explore how ghrelin, the hunger hormone, and its genetic variants influence type 2 diabetes risk, complications, and potential treatments.
Explore the fascinating relationship between traditional plant medicine and modern science in diabetes treatment. Discover historical uses, current research, and future perspectives.
Discover how γ-hydroxybutyrate (GHB) and glycine regulate glucagon secretion in pancreatic alpha cells and their role in diabetes pathophysiology.