Research Articles
Advanced Strategies for Preventing Insulin Pump Infusion Set Kinks and Blockages: A Research and Development Perspective
This article provides a comprehensive analysis of the mechanisms, prevention, and resolution of infusion set malfunctions, specifically kinks and blockages, which are prevalent causes of insulin delivery failure and hyperglycemia.
Hemoglobin Glycation Index (HGI): A Comprehensive Guide to Calculation, Application, and Clinical Validation for Advanced Glucose Control Assessment
This article provides a comprehensive analysis of the Hemoglobin Glycation Index (HGI), a significant biomarker that quantifies inter-individual variation in hemoglobin glycation.
Dual-Hormone Artificial Pancreas Systems: Overcoming the Limits of Single-Hormone AID in Type 1 Diabetes
This article comprehensively reviews the development of dual-hormone (insulin and glucagon) artificial pancreas systems for Type 1 Diabetes management.
Advanced Feature Engineering for CGM Time Series Data: From Fundamentals to Clinical Translation
This article provides a comprehensive guide to feature engineering for Continuous Glucose Monitoring (CGM) time series data, tailored for researchers, scientists, and drug development professionals.
Closed-Loop Control System Design for the Artificial Pancreas: From Foundational Algorithms to Clinical Implementation
This article provides a comprehensive review of the engineering and algorithmic foundations of Artificial Pancreas (AP) systems for automated glucose management in diabetes.
Ex Vivo Jejunal Sac Assay: A Comprehensive Guide to Measuring Glucose Absorption for Drug Discovery and Research
This article provides a detailed guide on the ex vivo everted jejunal sac technique, a fundamental tool for investigating intestinal glucose absorption mechanisms.
Mastering the Caco-2/TC7 Glucose Uptake Assay: A Comprehensive Guide from Foundations to Advanced Applications
This article provides a definitive guide to conducting in vitro glucose uptake assays using the human intestinal Caco-2/TC7 cell model.
The Sorensen Model: A Comprehensive Guide to High-Fidelity Glucose-Insulin Simulation for Biomedical Research
This article provides a comprehensive exploration of the Sorensen physiological model, a foundational yet complex multi-compartmental framework for simulating glucose-insulin dynamics.
Advances in CGM Sensor Error Analysis and Calibration Algorithms: A Technical Review for Biomedical Research
This article provides a comprehensive technical review of continuous glucose monitoring (CGM) systems, focusing on the sources of sensor error and the evolution of calibration methodologies.
Model Predictive Control for Blood Glucose Regulation: Algorithm Design, Clinical Validation, and Future Directions
This comprehensive review examines Model Predictive Control (MPC) algorithms for automated blood glucose regulation in type 1 diabetes.