Research Articles
Insulin's Multimeric Blueprint: A Structural Guide to Monomers, Dimers, and Therapeutic Hexamers
This comprehensive review dissects the structural architecture of insulin across its monomeric, dimeric, and hexameric states, detailing their biological relevance and therapeutic implications.
Akkermansia muciniphila and Insulin Sensitivity: A Comprehensive Review of Human Clinical Studies
This article provides a systematic review of human studies investigating the relationship between the gut commensal bacterium Akkermansia muciniphila and insulin sensitivity.
Bridging the Loop: Overcoming Coordination Failures Between Glucose Sensing and Insulin Delivery in Diabetes Management
This article examines the critical challenge of poor coordination between glucose monitoring and insulin injection, a persistent barrier to optimal glycemic control.
Delayed Hyperinsulinemia in PK Studies: Mechanisms, Measurement, and Mitigation Strategies for Drug Development
This article provides a comprehensive guide for researchers on delayed hyperinsulinemia in pharmacokinetic (PK) studies.
Maximizing Cellular Power: A Comprehensive Guide to ATP Production from Glucose via Oxidative Phosphorylation for Biomedical Research
This article provides a detailed, research-oriented analysis of ATP production through glucose-fueled oxidative phosphorylation (OXPHOS).
ARIMA vs Ridge Regression: Which Model Delivers Superior Accuracy for CGM Forecasting in Clinical Research?
This article provides a comprehensive comparative analysis of ARIMA (Autoregressive Integrated Moving Average) and Ridge Regression models for forecasting Continuous Glucose Monitoring (CGM) data, a critical task in diabetes research...
Optimizing Subcutaneous Drug Delivery: A Comprehensive Guide to 4mm Pen Needle Injection Protocol
This article provides a detailed scientific and procedural guide for the use of 4mm pen needles in subcutaneous drug delivery, aimed at researchers and drug development professionals.
16S rRNA Sequencing in Diabetes Microbiome Research: Methods, Challenges, and Clinical Insights
This article provides a comprehensive technical resource for researchers and drug development professionals exploring the gut microbiota's role in diabetes through 16S rRNA shotgun sequencing.
Calibration Science for Blood Glucose Meters: Principles, Protocols, and Future Directions for Biomedical Research
This article provides a comprehensive examination of blood glucose meter (BGM) and continuous glucose monitor (CGM) calibration for a scientific audience.
CGM Sensor Accuracy Comparison 2025: A Detailed Analysis for Biomedical Research and Drug Development
This article provides a comprehensive, evidence-based analysis of continuous glucose monitoring (CGM) sensor accuracy across leading brands and models, including Dexcom G7, Abbott FreeStyle Libre 3, and Medtronic Simplera.