Research Articles
The Unexpected Director: How a Cellular Power Player Guides Insulin Production
Discover how succinate, a key molecule in cellular energy production, regulates insulin secretion and proinsulin biosynthesis in pancreatic beta cells.
The Sweet Spark: How a Surprising Brain Chemical Supercharges Insulin
Discover how serotonin, the feel-good neurotransmitter, plays a crucial role in amplifying insulin secretion through the 5-HT2b receptor in pancreatic cells.
The Sugar Switch: How Estrogen Talks to Your Pancreas in Real-Time
Discover how estrogen's rapid insulinotropic effect works through plasma membrane receptors to regulate blood sugar in real-time.
The Secret Gatekeeper of Insulin: How the Sec61α2 Translocon Protects Against Diabetes
Discover how the Sec61α2 translocon serves as a specialized gateway for insulin biosynthesis and its implications for diabetes research and treatment.
The Sugar Highway: Navigating the Delicate Dance of Glucose in a Mouse's Body
Explore the fascinating world of glucose metabolism regulation in rodents and the groundbreaking techniques used to study it.
Beyond the Scale: Two Game-Changing Concepts of Fat Metabolism
Explore the science behind fat metabolism, including the insulin-glucagon switch and the difference between visceral and subcutaneous fat.
Biosimilars in Diabetes: The Revolution of Affordable Insulin Therapy
Explore how biosimilar insulins are transforming diabetes treatment by providing equally effective therapy at significantly lower costs, improving access worldwide.
The Brain's Hidden Sugar Superhighway: A Surprising Discovery in the Cerebellum
Discover how cerebellar neurons possess a vesicular compartment structurally and functionally similar to Glut4-storage vesicles from peripheral insulin-sensitive tissues
The Actin Orchestra: How Cellular Conductors Direct Insulin Secretion
Explore how actin dynamics regulated by N-WASP and cofilin balance determines the biphasic response of glucose-induced insulin secretion
The Glucose Seesaw: How Glucagon Fights Back During Insulin Therapy
Explore the intricate relationship between glucagon and insulin in blood sugar regulation, with clinical evidence showing glucagon's response during insulin infusion.